Lab News
November 20, 2023

4th "Systems Biology and Systems Physiology" meeting will take place at the Center for Theoretical Problems of Physico-Chemical Pharmacology on November 25, 2023
This year the meeting will be devoted to the Cytoskeleton. The program of the conference includes talks from Russian and international specialists in the fields of cellular motility, muscle contraction, tubulin cytoskeleton and cell division.
November 13, 2023

Nikita Gudimchuk will give a popular lecture on 'Molecular mechanisms of microtubule dynamics'
The lecture will take place at 17:00 on November 16 in the central auditorium of the Physics Deparment of Lomonosov Moscow State University. The lecture is open to the students and faculty of the Moscow State University.

October 18, 2023

Our paper is published in the European Journal of Cell Biology
Our work on "Microtubule rescue control by drugs and MAPs examined with in vitro pedestal assay" is available online as a part of the Special Issue of the European Journal of Cell Biology on "In vitro reconstitution of cytoskeletal processes"

October 13, 2023

Our new article is published in Biophysical reviews
This review is devoted to measuring and modeling forces generated by microtubules. The full text is here

July 7, 2023

Graduate students from our lab were awarded a medal prize from the Russian Academy of Sciences
Mikhail Anisimov and Veronika Alexandrova were awarded medals for young scientists in the area of physico-chemical biology for their work "Physico-chemical foundations of microtubule dynamic instability and its regulation". Congratulations!
April 23, 2023

We have attended the Congress of Russian Biphysicists

The 7th Congress of Russian Biophysicists was held in Krasnodar this year. Mikhail, Igor and Nikita gave three platform talks in the Molecular Biophysics section.

March 9, 2023

Head of our laboratory is celebrating his birthday today! Congratulations to Nikita!

We wish you dynamic tubulin and active proteins! Successful models! Satisfactory students! Good PhD students! Excellent PostDocs!
A grant for each gyrus!
An article for each glove!

July 1, 2022

The 1st CTP PCP RAS Summer School in Molecular Biology is over

We are happy to report that the past 5 days were quite intense, productive and successful. Together with 12 great students we performed gene cloning, transformation of bacterial cells, IPTG-induced gene expression and protein purification. As a result, three beautiful fluorescent proteins were produced and isolated.
June 10, 2022

Summer School in Molecular Biology: Applications are welcome!

Applications are accepted until June 22, 2022

School dates: from June 27 to July 1, 2022

June 9, 2022

The head of our laboratory, Nikita Gudimchuk has defended a Dr. of Science thesis

The defence of the thesis entitled "Microtubule dynamics and the mechanism of chromosome transport during cell division" (in Biophysics) took place at the Physics Department of Lomonosov Moscow State University. An excellent microtubule cake was awarded and eaten together

August 19, 2021

A paper with our contribution is published in J.A.C.S.!

We were lucky to make our modest contribution to the extensive study conducted by chemists at Moscow State University and Florida State University, USA: Expanding Stereoelectronic Limits of endo-tet Cyclizations: Synthesis of Benz[b]azepines from Donor-Acceptor Cyclopropanes. Our contribution to this work was to determine the effects of completely new compounds synthesized for this study on the microtubules dynamics in vitro.
The author of the picture below is Maria Andreeva

August 18, 2021

Our review on the roles of microtubule tips is published in Nature Reviews Molecular Cell Biology!
In this work, we tried to address issues related to the physiology of a wide range of processes associated with the microtubule dynamics, and to formulate modern ideas about the mechanisms and regulation of the microtubules dynamics in cells and artificial systems:Regulation of microtubule dynamics, mechanics and function through the growing tip

Our paper is on December cover!

July 24, 2021

We have attended the European Biophysical Congress in Vienna, Austria!

The conference was especially enjoyable and long-awaited as it was the first opportunity to meet face-to-face with scientists from all over the world since the outbreak of the pandemic.
Special congratulations to Veronika Alexandrova, who received the Biophysical Society award for the best poster presentation!
Mikhail Anisimov and Iuliia Lopanskaya have received EBSA Travel Awards
May 21, 2021

Our collaboration project with Antonina Roll-Mecak lab is published in Developmental Cell!

We have shown that the unstructured C-tails of alpha-tubulin can directly regulate microtubule dynamics. Detyrosination of alpha-tubulin C-tails affects microtubules only indirectly, modulating the binding of regulatory protein CLIP-170 to the microtubules. Below is a video showing the calculation results of the interaction between alpha-tubulin C-tail and its globule. On the left is a picture drawn by a first author, Jiayi Chen, of comets formed by plus-end binding proteins, presented on the cover of Dev Cell!
April 25, 2021

Our article took 2nd place in the Bio/Mol/Text competition 2021!

Congratulations to Mikhail Anisimov and Nikita Gudimchuk, who took the second place in the "Biomolecula" contest with the article "Zoo of tubulin inhibitors".
March 31, 2021

Our article is now published in SBP Reports!

An article on statistical processing of biological data titled Avoiding common problems with statistical analysis of biological experiments using a simple nested data simulator is published in a journal of Systems Biology and Physiology Reports